biomarin field trip reflection
At Biomarin, they research the enzymes that break down waste. There are many genetic diseases (lysosomal storage diseases) in which people do not produce a certain enzyme, so waste stays in their cells and the cells die.
I don't know how to organize my thoughts but here are some words
spectrometer- detect & measure protein
HPLC- high performance liquid chromatography- analytic chemistry- used to separate, identify, and quantify each component in a mixture
protein purification- after the drug is created, it has to be separated from water, etc
chromatography columns- used in purification
protein charge-
analytical chemistry- protein characterization
lysosomal storage diseases- certain waste proteins are stored in the lymph cells because the enzyme that breaks them down is not produced. this kills the cells
CHO cells- Chinese hamster ovary- the living cells that are tested on, human DNA is put in them
autoclaving for sterilization- an autoclave is a pressure chamber, steam is put in and pressurized in order to kill bacteria
bioreactor- to stimulate an organ, tissue, or cells being inside a human body
laminar flow hood- a workspace to make sure there is no bacteria
cell culture incubator- maintains temperature, humidity, and oxygen content
Their main goal is to maximize shareholder value.
I learned that human cells divide themselves every 24 hours, but bacteria divides in 14 minutes, NOT 20 hours or 2 weeks for humans and 20 minutes for bacteria, Ms. Flasher.
I mostly just want to go back to look at all the silly machine names
like "puppy"
I would like to go back once I understand what the machines do, what components different cells and enzymes have and how that helps to separate different types.
I don't know how to organize my thoughts but here are some words
spectrometer- detect & measure protein
HPLC- high performance liquid chromatography- analytic chemistry- used to separate, identify, and quantify each component in a mixture
protein purification- after the drug is created, it has to be separated from water, etc
chromatography columns- used in purification
protein charge-
analytical chemistry- protein characterization
lysosomal storage diseases- certain waste proteins are stored in the lymph cells because the enzyme that breaks them down is not produced. this kills the cells
CHO cells- Chinese hamster ovary- the living cells that are tested on, human DNA is put in them
autoclaving for sterilization- an autoclave is a pressure chamber, steam is put in and pressurized in order to kill bacteria
bioreactor- to stimulate an organ, tissue, or cells being inside a human body
laminar flow hood- a workspace to make sure there is no bacteria
cell culture incubator- maintains temperature, humidity, and oxygen content
Their main goal is to maximize shareholder value.
I learned that human cells divide themselves every 24 hours, but bacteria divides in 14 minutes, NOT 20 hours or 2 weeks for humans and 20 minutes for bacteria, Ms. Flasher.
I mostly just want to go back to look at all the silly machine names
like "puppy"
I would like to go back once I understand what the machines do, what components different cells and enzymes have and how that helps to separate different types.